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Beta cells ( β-cells ), are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. [1] Constituting ~50-70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. [2]


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The nucleus is an organelle that contains a cell's genes. Chloroplasts are organelles that carry out photosynthesis, which makes the food plant cells need to live. This food is in the form of sugars. Plant cells have chloroplasts and a cell wall, but animal cells do not.


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Pancreatic β-Cell Development and Regeneration. 2022 May 27;14 (5):a040741. doi: 10.1101/cshperspect.a040741. The pancreatic β-cells are essential for regulating glucose homeostasis through the coordinated release of the insulin hormone. Dysfunction of the highly specialized β-cells results in diabetes mellitus, a growing global health epidemic.


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There are two main types of B-cells: plasma cells and memory cells. Both types help protect you from infection and disease. Plasma cells: Plasma cells release antibodies in response to antigens. Once a B-cell becomes a mature plasma cell, it can release up to 2,000 antibodies per second. Plasma cells are also called plasmacytes or effector cells.


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The Jurkat cell line is an immortalized T lymphocyte cell line that was originally obtained from the peripheral blood of a boy with T cell leukemia [14 ].


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2.1 Properties of EVs. EVs, a heterogeneous family of membrane-limited vesicles originating from the endosome or plasma membrane, can be divided into three types according to size (Abels and Breakefield, 2016).Apoptotic bodies, ranging from 800 to 5,000 nm, are produced by shedding cells during apoptosis, while microvesicles with a 200-2000 diameter are produced by the plasma membrane in a.


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Twenty years of investigation have yielded a detailed view of the signalling machinery engaged by T-cell receptors (TCRs). Many of the fundamental insights into TCR signalling came from studies.


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Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. [1]